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The Roybal Center for Elder Mistreatment Intervention Research is pleased to announce a call for applications for projects aimed at advancing research on interventions for elder mistreatment (EM), including (a) interventions to prevent EM and (b) interventions to prevent the negative health and mental health consequences of EM. The Center is designed to overcome crucial barriers that have historically prevented significant, impactful progression of EM intervention development research, and to assist investigators in building sustainable EM research programs.


Application due:  February 12, 2025

Background

EM, including financial exploitation, neglect, self-neglect, and various forms of abuse, affects a significant portion of older adults living in the community (over 15%) and an even greater number of persons living with Alzheimer’s Disease and Related Dementias (over 50%). Despite the negative outcomes associated with EM, evidence-based guidelines for prevention and management are lacking. The UTHealth Roybal Center for Elder Mistreatment Intervention Research aims to address this lack of available interventions by supporting innovative projects that advance the field of EM research through mechanisms-focused interventions.


Eligibility

We invite proposals from new and new-to-the-field investigators who intend to develop or adapt evidence-based interventions from related fields that target known EM risk factors or outcomes through a clearly defined mechanism. Interventions can target either the caregivers at risk for engaging in EM or the older adults at risk for experiencing EM. Eligible applicants must be independent researchers with faculty appointments at the time the award will be made. Applicants must also include a letter of support from their department chair confirming their availability of release time if funded.

Proposals must focus on stages 0-2 of the NIH Stage Model of Behavioral Intervention Development and must be supported by a clearly defined mechanism. All proposed projects must be a clinical trial with adequate statistical power to test mechanisms of behavior change and/or the efficacy of the intervention. We understand that not all scientists get extensive training in trial design and power analysis, which can be a barrier to submitting a proposal. However, we don’t want this to be a barrier for you. We can connect you with experts who can assist you with these elements of your proposal. 


Research Focus  

We encourage applications that address:

  • Adaptation of evidence-based interventions to target known EM risk factors or outcomes.

  • Development and initial testing of behavioral intervention mechanisms.

  • Innovative approaches to real-world testing and collaboration with service providers.

Applicants will be judged as non-responsive if:

  • They do not have a primary focus on behavioral and/or social intervention development.

  • They are not focused on supporting community-dwelling older adults or their caregivers in the prevention or reduction of EM and its outcomes. Proposals focused on long-term care settings are outside the scope of this solicitation.

  • They do not address stage 0-2 of the NIH Stage Model of Behavioral Intervention Development.

  • Applications that do not state and propose to test, within their Specific Aims, hypotheses regarding the mechanism of behavior change of interventions for each of the clinical trials proposed.

     

Funding Details
  • Amount: The Center intends to commit $300,000 in total costs each year to fund 1-3 awards.

  • Duration: The Center will consider projects that are up to 2 years in length.

  • Indirect costs: All project budgets should be inclusive of indirect costs. We strongly encourage applicants to seek IDC waivers to maximize the direct costs available to projects.

  • Format: Proposals must adhere to the R03 grant format guidelines.

  • Support Requirements: If your project involves university cores, services, or external recruitment sites (e.g., bioinformatics support for electronic health record data), please include appropriate letters of support.


Mentorship and Support

To ensure the progression of successful interventions, the selected project proposals will benefit from guidance provided by the UTH Roybal Cores, the Evaluation Committee, and the External Advisory Committee. This will include help working with service providers such as Adult Protective Services, securing testing sites, and navigating IRB requirements. A formal mentor or training plan is not required.


Submission Instructions

Please submit a one-page specific aims page directly to Drs. Acierno and Cannell (contact information below or at right) before submitting a full application.

Applications should be submitted electronically to the School of Nursing grants management office. Proposals must adhere to the R03 format guidelines and include all necessary letters of support.




The NBER Roybal Center for Behavior Change in Health seeks proposals for research projects that involve randomized controlled trials (RCTs) or other NIH-defined clinical trials, and that, if approved for funding by the National Institute on Aging (NIA), would receive support during the period June 1, 2025 through May 31, 2026. Eligible projects must explore some aspect of the relationship between health and human behavior and must be adequately powered to detect meaningful treatment effects. Potential project funding is likely to fall in the range of $175,000 to $260,000 of direct costs.


Is your project an NIH-defined clinical trial? The answers to the following four questions must be “yes”:
  1. Does the study involve human participants?

  2. Are the participants prospectively assigned to an intervention?

  3. Is the study designed to evaluate the effect of the intervention on the participants?

  4. Is the effect being evaluated a health-related biomedical or behavioral outcome?


     

Proposals will be evaluated by the Center co-PIs (Marcella Alsan and Joseph Doyle) and Advisory Committee for research design, relevance, feasibility, scalability, and timeliness. We look for projects that propose to test scalable interventions with the potential to broadly improve population health as people and prioritize those with the potential to advance through the NIH Stage Model for Behavioral Intervention Development. Projects that evaluate mechanisms of behavior change are of particular interest.


To be eligible for support, subject recruitment for the study may not have started yet, and it must be possible to delay recruitment until after formal NIH approval.  The project must comply with all NIH clinical trial policies.

We welcome proposals from affiliates and non-affiliates, junior researchers, and scholars who are members of groups that are under-represented in the economics profession.


Please direct questions to the Associate Director of the NBER Roybal Center, Sarah Holmes Berk (sholmes@nber.org, 617-588-1445). 

Next steps / How to apply: 
  • This summer/fall:  Reach out to us about potential project ideas and determine suitability for an application.

  • By Monday, January 6, 2025: Submit a brief description of your project (including power calculations) and anticipated budget needs. Upload a PDF with this information here.

  • By Friday, January 24, 2025: We will tell you if we are able to include your project.

  • By Monday, February 24, 2025: Using templates and instructions we will provide, submit your Specific Aims, 2-page Research Design, Human Subjects Questionnaire, Planned Inclusion Enrollment Report(s), Budget, Biosketch, and Other Support.

  • During March 2025: Review and approve your Human Subjects System record, which we will draft. Complete applicable NBER and NIH administrative requirements.

  • Summer 2025: We will learn if your study has been approved by the NIH. Depending on the risks associated with your study, the NIH may require your study to receive Data & Safety Monitoring Board (DSMB) and/or Safety Officer (SO) approval before recruitment can begin.

  • For as long as your study continues: Update us periodically on your progress. If applicable, update the DSMB and/or SO periodically and submit monthly enrollment data to NIA. Help us maintain your ClinicalTrials.gov and Human Subjects System records.

  • The University of Illinois Chicago (UIC) Midwest Roybal Center for Health Promotion and Translation seeks to advance the science, translation, and practice of health promotion programs for underserved older adults at risk of Alzheimer’s Disease and Alzheimer’s Disease Related Dementias (AD/ADRD) in order to improve the functioning and quality of life of this growing segment of our population.



The Midwest Roybal Center is holding a competition that will review and award up to 2 randomized controlled trials. Trials will begin June 1, 2025. Projects can be funded for up to $200K direct total for 1 or 2 years.


LOI:  December 9, 2025
Final proposal due (if selected):  January 20, 2025

The University of Illinois Chicago (UIC) Midwest Roybal Center for Health Promotion and Translation seeks to advance the science, translation, and practice of health promotion programs for underserved older adults at risk of Alzheimer’s Disease and Alzheimer’s Disease Related Dementias (AD/ADRD) in order to improve the functioning and quality of life of this growing segment of our population.


Application Details:

The Midwest Roybal Center will award applications that successfully:

  • Include interventions that prevent or delay cognitive decline and AD/ADRD that:

    • Target mechanisms of behavior change to promote behavioral and lifestyle change in individuals or groups at risk of cognitive decline and AD/ADRD AND/OR

    • Spur the initiation and maintenance of physical activity regimens to prevent or delay cognitive decline and/or AD/ADRD that are personalized to individuals or groups who share specific characteristics and/or preferences AND/OR

    • Leverage technology to prevent or delay cognitive decline and/or AD/ADRD

  • Have a primary focus on behavioral and/or social intervention development.

  • Focus on mid-life and older individuals.

  • Have goals to improve the health and well-being of people living with dementia (PLWD), or with a focus on behavioral and/or social interventions to prevent or delay cognitive decline and/or AD/ADRD.

  • Specify, within their Specific Aims, the Stage of research, as defined by the NIH Stage Model, for the clinical trial proposed.

  • State and propose to test, within their Specific Aims, hypotheses regarding the mechanism of behavior change of interventions for the clinical trial proposed.

  • Have the goal of serving as inclusive a population as possible, and applicants are required to describe how they will recruit participants from minority health and health disparity populations.

  • Address issues of statistical power for proposed clinical trials. All clinical trials must have adequate statistical power to test mechanisms of behavior change and/or efficacy of the intervention. This includes Stage I “pilot” testing studies that include a specific aim to test the efficacy of an intervention, or the mechanism of behavior change of an intervention.


Awardees are expected to participate in Midwest Roybal Center activities pertaining to research, education, and service and will be expected to make brief presentations to the Center Executive and Advisory Committees during the course of the RCT and upon its completion. Awardees must comply with NIH and NIA reporting requirements e.g., ClincalTrials.gov and CROMS. Funded RCTs may also be required to participate in an NIH data sharing plan and in a Center Data Safety Monitoring Committee.


Eligibility:

Open to all US research and clinical faculty.


Submit LOI here (users will need to create an InfoReady account).

 


Questions? Email Andrew DeMott, ademot1@uic.edu



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